代谢调控结构生物学研究

男

副研究员

lijx@cemps.ac.cn

上海松江区辰花公路3888号 上海辰山植物园科研中心/中国科学院分子植物科学卓越创新中心辰山科学研究中心

201602

植物代谢与结构生物学

（1）植物代谢中关键酶的催化与调控机制解析；

（2）植物代谢酶的理性设计与合成生物学应用。 

中国科学院青年创新促进会会员，赛诺菲-中国科学院上海生命科学研究院优秀青年人才奖，上海市东方英才计划乡村振兴青年英才

2001年-2005年，山东师范大学，学士学位；

2005年-2012年，中国科学院植物生理生态研究所，博士学位；

2012年-2015年，美国加州大学伯克利分校和中科院植生所，博士后；

2015年-2017年，中国科学院植物生理生态研究所，助理研究员；

2017年-至今，中国科学院分子植物科学卓越创新中心，副研究员；

2021年-至今，中国科学院分子植物科学卓越创新中心，特聘骨干；

2023年-至今，上海辰山植物园/中国科学院分子植物科学卓越创新中心辰山科学研究中心，青年课题组长

1. Ni, Rong#; Niu, Meng#; Fu, Jie; Tan, Hui; Zhu, Tingting; Zhang, Jing; Lou, Hongxiang; Zhang, Peng; Li, Jianxu*; Cheng, Aixia*; Molecular and structural characterization of a promiscuous chalcone synthase from the fern species Stenoloma chusanum, Journal of Integrative Plant Biology, 2022, 64: 1935-1951.

　　2. Wang, Chengyuan#; Li, Jianxu#; Ma, Miaolian; Lin, Zhaozhu; Hu, Wenli; Lin, Wei*; Zhang, Peng*; Structural and Biochemical Insights Into Two BAHD Acyltransferases (AtSHT and AtSDT) Involved in Phenolamide Biosynthesis, Frontiers in Plant Science, 2021, 11: 610118.

　　3. Yao, Yuanfa#; Li, Jianxu#; Lin, Yinyan#; Zhou, Jiaqiang; Zhang, Peng*; Xu, Yingke*; Structural insights into phospholipase D function, Progress in Lipid Research, 2021, 81: 101070.

　　4. Niu, Meng#; Fu, Jie#; Ni, Rong; Xiong, Ruilin; Zhu, Tingting; Lou, Hongxiang; Zhang, Peng; Li, Jianxu*; Cheng Aixia*; Functional and structural investigation of chalcone synthases based on integrated metabolomics and transcriptome analysis on flavonoids and anthocyanins biosynthesis of the fern Cyclosorus parasiticus, Frontiers in Plant Science, 2021, 12: 757516.

　　5. Li, Jianxu#; Yu, Fang#; Guo, Hui; Xiong, Renxue; Zhang, Wenjing; He, Fangyuan; Zhang, Minhua; Zhang, Peng*; Crystal structure of plant PLDa1 reveals catalytic and regulatory mechanisms of eukaryotic phospholipase D, Cell Research, 2020, 30(1): 61-69.

　　6. Chen, Qingwen#; Li, Jianxu#; Liu, Zhixi#; Mitsuhashi, Takaaki; Zhang, Yuting; Liu, Haili; Ma, Yihua; He, Juan; Shinada, Tetsuro; Sato, Tsutomu; Wang, Yong; Liu, Hongwei; Abe, Ikuro; Zhang, Peng*; Wang, Guodong*; Molecular Basis for Sesterterpene Diversity Produced by Plant Terpene Synthases, Plant Communications, 2020, 1(5): 100051. (Cover story)

　　7. Liu, Zhifeng#; Li, Jianxu#; Sun, Yuwei#; Zhang, Peng*; Wang, Yong*; Structural Insights into the Catalytic Mechanism of a Plant Diterpene Glycosyltransferase SrUGT76G1, Plant Communications, 2020, 1(1): 100004.

8. Song, Jiaojiao#; Fang, Xin#; Li, Chenyi; Jiang Yan; Li, Jianxu; Wu, Sheng; Guo, Juan; Liu, Yan; Fan, Hang; Huang, Yanbo; Wei, Yukun; Kong, Yu; Zhao, Qing; Xu, Jingjing; Hu, Yonghong; Chen, Xiaoya; Yang, Lei*; A 2-oxoglutarate-dependent dioxygenase converts dihydrofuran to furan in Salvia diterpenoids, Plant Physiology, 2022, 188: 1496-1506.

　　9. Xu, Jingjing#; Zhang, Xiaofan#; Yan, Jiang; Fan, Hang; Li, Jianxu; Li, Chenyi; Zhao, Qing; Yang, Lei; Hu, Yonghong; Martin, Cathie; Chen, Xiaoya*; A unique flavoenzyme operates in ubiquinone biosynthesis in photosynthesis-related eukaryotes, Science Advances, 2021, 7: eabl3594.

　　10. Chen, Qingwen; Li, Jianxu; Ma, Yihua; Yuan, Weiliang; Zhang, Peng; Wang, Guodong*; Occurrence and biosynthesis of plantsesterterpenes (C25), a new addition to terpene diversity, Plant Communications, 2021, 2: 100184.

　　11. Cui, Mengying; Lu, Anrui; Li, Jianxu; Liu, Jie; Fang, Yumin; Pei, Tianlin; Zhong, Xin; Wei, Yukun; Kong, Yu; Qiu, Wenqing; Hu, Yonghong; Yang, Jun; Chen, Xiaoya; Martin, Cathie; Zhao Qing*; Two types of O-methyltransferase are involved in biosynthesis of anticancer methoxylated 4’-deoxyflavones in Scutellaria baicalensis Georgi, Plant Biotechnology Journal, 2021, 20: 129-142.

　　12. Huang, Jinquan#; Fang, Xin#; Tian, Xiu; Chen, Ping; Lin, Jialing; Guo, Xiaoxiang; Li, Jianxu; Fan, Zhen; Song, Weimeng; Chen, Fangyan; Ahati, Ruzha; Wang, Lingjian; Zhao, Qing; Martin, Cathie; Chen, Xiaoya*; Aromatization of natural products by a specialized detoxification enzyme, Nature Chemical Biology, 2020, 16(3): 250-256.